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I'm not sure what you mean by harmful but different publications (like Oprah's Book Club versus a regular printing) of the book will have different ISBN numbers. The stories are exactly the same though.

Usually this means that the edition is different or they changed a few things. I know i bought a math book online that was cheaper and had a different ISBN number and about half way through the year the problems the teacher assigned didn't correspond with the problems in my book. So when i got back my assignments i had received a 0 but luckily she was understanding and worked with me on it. Just be careful