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Ear Force PX5 Programmable Wireless 7.1 Dolby Digital Surround Sound Headset with Bluetooth is my first gaming headset. I based my decision on the feedback left here on amazon and turtle beach website. I think these are incredible the soundis amazing. Worth every penny. I have it lnked to my cell when gaming so when my mom calls me ( she's long winded) I'm gaming hearing the sounds of gunfire and she doesent hear a thing lol. Great buy, no issues with reception, my px5 is next to my wreless Verizon router. No issues. You get what you pay for.

It has nothing to do with the headset. The PX5 doesn't know which game you're playing, so if it works for other games it has to work for Uncharted. Check if the PX5 is working with another game. If it is, then check the audio settings on Uncharted. Maybe you don't have it set to Dolby 5.1 so it's not sending a signal to the PX5 transmitter. Also, try changing the batteries in the PX5.